|
Grant Community.com Catalog of Federal Domestic Assistance Program Descriptions |
CATALOG OF FEDERAL DOMESTIC
ASSISTANCE
93.306: Comparative Medicine
|
| PROGRAM AND AWARD | FINANCIAL AND INFORMATION CONTACTS |
| ELIGIBILITY REQUIREMENTS | FINANCIAL AND ADMINISTRATIVE INFO. |
| APPLICATION AND AWARD PROCESS | INFORMATION CONTACTS |
| RELATED PROGRAMS | ASSISTANCE CONSIDERATIONS |
| PROGRAM ACCOMPLISHMENTS | POST ASSISTANCE REQUIREMENTS |
Applicant Eligibility: Institutions of higher education, hospitals, and other institutions and organizations, both nonprofit and for-profit, seeking to establish, continue, or enlarge programs consistent with the objectives of the program. Applicants for NRSA must be citizens of the United States or be admitted to the United States for permanent residency. Applicants must be nominated and sponsored by a public or private nonprofit institution with staff and facilities suitable for the proposed research training. Nonprofit domestic organizations may apply for the institutional NRSA. To be eligible, post-doctoral awardees must have a professional or scientific degree (M.D., Ph.D., D.V.M., D.D.S., or equivalent degree). SERCA awardees must have a degree in veterinary medicine (D.V.M. or equivalent) and 3 years of post-doctoral experience in comparative medicine or comparative pathology areas. To be eligible for funding, the grant application must be approved for scientific merit and program relevance by a scientific review group and the national advisory council.
Beneficiary Eligibility: Investigators at for-profit and nonprofit hospitals, institutions of higher education, and other research institutions and organizations.
Credentials/Documentation: None is required for research grants. Individual NRSA grants require that the applicant's academic record, research experience, citizenship, institutional sponsorship, etc., be documented in the application form supplied by the Center for Scientific Review, National Institutes of Health. Institutional NRSA Grants require the institution to show the objectives, methodology and resources for the research training program, the qualifications and experience of directing staff, the criteria to be used in selecting individuals for award, and a detailed budget and justification for the grant funds requested. Costs will be determined in accordance with HHS Regulations 45 CFR, Part 74, Subpart Q, OMB Circular No. A-122, "Cost Principles for Nonprofit Organizations," OMB Circular A-21 for Educational Institutions, and OMB Circular No. A-87 for State and local governments. For-profit organizations' costs are determined in accordance with 48 CFR, Subpart 31.2 of the Federal Acquisition Regulations and 45 CFR, Part 92 for nonprofit organizations.
Preapplication Coordination: Not applicable. This program is excluded from coverage under E.O. 12372.
Application Procedure: Application forms may be obtained from the Division of Extramural Outreach and Information, 6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910. Phone (301) 435-0714, e-mail: grantsinfo@nih.gov. Completed applications should be submitted to the Center for Scientific Review, 6701 Rockledge Drive, MSC 7710, Bethesda, MD 20892-7710. The standard application forms PHS 398, (Rev. November 1998), as furnished by PHS and required by 45 CFR, Part 92, must be used for this program. For filing NRSA individual fellowship award applications, Form 416-1 (Rev. October 1991) is needed. Prior to formal application, the applicant for a NRSA must arrange for acceptance at a sponsoring institution by a mentor who will supervise the training. Individual National Research Service Awards may be sponsored by a domestic or foreign nonprofit organization. This NRSA program is subject to the provisions of 45 CFR, Part 92 for State and local governments and OMB Circular No. A-110 for nonprofit organizations.
Award Procedure: Applications from eligible investigators and institutions are initially reviewed by study sections and review committees comprised of authorities in various fields of biomedical research. Each application is given a peer evaluation for merit, and recommendations are forwarded to the National Advisory Research Resources Council for review and final recommendations.
Deadlines: New Grant Applications: February 1, June 1, and October 1. Competing Renewal Grant Applications: March 1, July 1, and November 1. NRSA Applications: Individual Fellowships - April 5, August 5, and December 5.
Range of Approval/Disapproval Time: From 6 to 9 months.
Appeals: A principal investigator (P.I.) may question the substantive or procedural aspects of the review of their application by communicating with NCRR staff. A description of the NIH Peer Review Appeals procedures is available on the NIH home page grants.nih.gov/grants/peer/peer.htm.
Renewals: Renewal applications are required every 1 to 5 years, depending on the grant. Council approval is required. Fellowship awards may be made for 1, 2, or 3 years. NIH fellowship support at the post-doctoral level is limited to 3 years. SERCAs are limited to 5 years.
Criteria for Selecting Proposals: The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives.
Examples of Funded Projects: Seven Regional Primate Research Centers are supported to provide special environments in which multi-disciplinary health-related research is conducted with nonhuman primate models. They maintain colonies of over 18,000 animals, representing 32 species of nonhuman primates, for research and breeding purposes. Projects for the characterization and development of animal models were supported, but were limited to those that displayed potential for multi-categorical utilization. Projects that attempt to establish an animal model for a specific disease should be directed to the Institute/Center/Division of NIH that supports categorical research in that area. The etiology and control of important naturally-occurring laboratory animal diseases have been studied. Biological Models and Materials Research Resource centers were supported to provide a large variety of materials to the research community. These centers acquire, authenticate, maintain, and distribute biomaterials to both basic researchers and clinical investigators. For example, resources distribute invertebrates (such as squid, mollusks, and nematodes), cultures of microorganisms, cell lines, fungi, yeast, hybridomas, cloned genes, DNA probes and libraries, and recombinant DNA and oncogenes. Also supported is a project to collect data on the genes and metabolism of the bacterium Escherichia coli and to encodethis information in a computer database that allows investigators to access genetic metabolic data in a graphic, user-friendly manner.
Range and Average of Financial Assistance: Regional Primate Research Centers: $200,429 to $10,586,146; $7,152,625. Animal resource and resource related grants: $44,753 to $1,749,444; $551,294. Research project grants: $22,660 to $780,838; $285,237. SERCA: $77,318 to $125,361; $109,850. Training and fellowship awards: $34,966 to $305,214; $166,476.
In fiscal year 1999, support was provided for eight Regional Primate Research Centers, 65 animal resource and resource related grants; 80 research project grants, 20 Special Emphasis Research Career Awards (SERCA and 21 training and fellowship awards. In fiscal year 2000, it is estimated that support will be provided for eight Regional Primate Research Centers, 69 animal resource and resource related grants, 85 research project grants, 28 SERCA, and 21 training and fellowship awards. In fiscal year 2001, support is planned for eight Regional Primate Research Centers, 69 animal resource and resource related grants, 93 research project grants, 28 SERCA, and 21 training and fellowship awards.
Federal Agency: NATIONAL INSTITUTES OF HEALTH, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Type of Assistance: Project Grants.
Obligations: (Grants) CM: FY 99 $112,902,000; FY 00 est $119,984,000; and FY 01 est $128,666,000.
Budget Account Number: 75-0848-0-1-552.
Authorization: Public Health Service Act, Titles III and IV, Sections 301, 479, 480, and 487, as amended; Public Laws 78-410 and 99-158, 42 U.S.C. 241, 287, 287a, and 288, as amended; Small Business Research and Development Enhancement Act of 1992, Public Law 102-564.
Regulations, Guidelines, and Literature: OMB Circular No. A-21, "Cost Principles for Educational Institutions." Reference: 44 FR 12368, March 6, 1979; Rev. No. 1, 47 FR 33658, August 3, 1982; Rev. No. 2, 51 FR 20908, June 9, 1986. OMB Circular No. A-110, "Grants and Agreements with Institutions of Higher Education, Hospitals, and Other Nonprofit Organizations." Reference: 41 FR 32016, July 30, 1976. OMB Circular No. A-122, "Cost Principles for Nonprofit Organizations." Reference: 45 FR 46022, July 8, 1980. 45 CFR 74; 45 CFR 92; 42 CFR 66; 42 CFR 52h. Department Staff Manual "Grants Administration"; Indirect Cost Register, PHS Grants Policy Statement, DHHS Publications No. (OASH) 94-50,000 (Rev.) April 1, 1994. "NIH Grants Policy Guide," Office for Protection from Research Risks, NIH; "A Guide to Grant and Award Programs of the NIH"; "Comparative Medicine Program Information for Applicants"; and miscellaneous program guidelines and literature are available from the Headquarters Office.
Regional or Local Office: Not applicable.
Headquarters Office: Contact: Director, Comparative Medicine. Phone: (301) 435-0744. National Center for Research Resources, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892. Grants Management Contact: Grants Management Officer, Office of Grants and Contracts Management, National Center for Research Resources, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892. Phone: (301) 435-0844. Use the same phone number for FTS.
(See Appendix IV for more contact info.)
Formula and Matching Requirements: This program has no statutory formula or matching requirements.
Length and Time Phasing of Assistance: From 1 to 5 years before renewal. SERCAs are limited to 5 years of support.
Uses and Use Restrictions: CM funded activities may include projects in the following areas of emphasis: (1) Biotechnology (improvement of transgenic technology, cryopreservation methods, and reproductive performance); (2) normative biology (animal genetics, animal behavior, identification and characterization of non-traditional species for research, animal nutrition, and reproductive biology); (3) animal disease (detection and characterization of diseases that interfere with research and threaten animal welfare; drug and vaccine development; and development of animals genetically resistant to disease); (4) animal welfare (improved methods of evaluating and alleviating pain, distress, and discomfort; environmental enrichment; and improved housing and husbandry technology); and (5) mammalian and non-mammalian models (continued discovery and development of natural and induced models of human biology and disease). Projects include support for the seven Regional Primate Research Centers; resource projects to develop and maintain special colonies of laboratory animals; Special Emphasis Research Career Awards (SERCA) in comparative medicine; and National Research Service Awards (NRSA) to individuals for post-doctoral training in the field of comparative medicine. Funded activities may also include projects and centers to develop and support non-mammalian models for biomedical research, which include cell systems, lower organisms (poikilotherms) and nonbiological systems; and resources that provide materials for the research community. The goals of the Small Business Innovation Research (SBIR) Program are to increase private sector commercialization of innovations derived from Federal research and development; to increase small business participation in Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. The goals of the Small Business Technology Transfer (STTR) Program are to stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer between small business concerns and research institutions; to increase private sector commercialization of innovations derived from Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation.
Reports: Progress reports and financial status reports are required to be submitted within 90 days of the end of the budget period. Final performance and financial status reports are required 90 days following the end of the project period. Reports are required after termination of NRSA to ascertain compliance with the service and payback provisions.
Audits: In accordance with the provisions of OMB Circular No. A-133 (Revised, June 24, 1997), "Audits of States, Local Governments, and Non-Profit Organizations," nonfederal entities that receive financial assistance of $300,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Nonfederal entities that expend less than $300,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in Circular No. A-133. In addition, grants and cooperative agreements are subject to inspection and audits by DHHS and other Federal government officials.
Records: Expenditures and other financial records must be retained for 3 years from the day on which the grantee submits the last expenditure report for the report period.
About
News Grant
Management Software Federal
Grant Programs Audits
Studies Expenditures
Links
Last Updated, November, 2000
Comments or Questions? ©Grant
Community.com 2000, All Rights Reserved